Originally Posted by Lemurion
Speaking specifically of North American comics, their print aspect ratio is 3:2 (15:10) so when viewing a single page in portrait 16:10 is better than 4:3. Where the iPad really shines though, is with double-page spreads because they are in a 4:3 landscape orientation.
Still, for most comic readers a large 16:10 HD screen is the best available option.
Size-wise, I actually prefer the Nexus 7 1280*800 for reading in portrait. Maybe if the 10" tablets get a significant weight reduction, I'd like them better. For double-page spreads, though, I agree that 4:3 works best. However, I'm not sure if a 7.9" display even with retina would be comfortable enough for reading comics in double-page landscape mode. 16:10 could still have been okay for landscape but the issue with new Android tablets with ICS/JB is you don't get access to the full 16:10 resolution because of the status and navigation bars. That said, Apple's closed system is quite stifling so I've actually been looking into Android tablets with 4:3 2048*1536 displays. Right now, that's mostly China tabs but Archos is releasing a dual-core 9.7" Titanium HD and has announced a quad-core 9.7" Platinum HD. I don't think performance of either is quite up to snuff just yet but I give it a year or so and I expect we'll see inexpensive chipsets capable of driving FullHD or retina display resolution.
I find the iPad Mini very interesting primarily due to its weight. If Apple manages to maintain weight and battery life with a retina display version, it's a maybe leaning strongly towards yes.