Yes, Stanza will suffer from that move. 3 out of 4
Settings buttons will stop working.
However, just forget about Stanza on the iPad. Stanza already has the successor:
Marvin. Marvin is not just Stanza's successor, but today it's already much, much better than Stanza ever was. You will find virtually everything you love about Stanza, in Marvin. Check it out here:
http://bit.ly/GetMarvin
http://www.marvinapp.com
http://www.marvinapp.com/whatsnew.html