Originally Posted by theducks
If those are your preferences, then stick to Portable and live with 32bits (which ain't that bad)
Well, many non portable apps allow you to take the files from somewhere else or to save them somewhere else, most of the ones I use do. Take like iTunes or Dropbox that both allow you to create folders or make backup wherever you want, which I do on a different partition. It's just a matter of adding it in the options.
As for me, I'd like to at least try out the 64 bits version of Calibre but I really dislike apps when they don't allow me to have the important files, save the files, or make backup where I want in my computer, usually not on C that is for sure. It's not safe.