Originally Posted by mrmikel
The catch is the now seemingly infinite number of readers and the lack of preview software for every single one of them (like grains of sand on the seashore!)
And that preview software, when available, sometimes doesn't accurately emulate layout on the physical device anyway!
If portability is required, the only thing you can realistically do is simply pour the text in. Let the reader determine how to treat paragraph breaks, whether to justify, serif or sans-serif.
This, however, doesn't seem to be what the market wants :-) Having enjoyed themselves agonising over niceties of layout in a printed edition, "take what you get" isn't what authors want to hear.