I'd like to nominate The Revenge of the Radioactive Lady
by Elizabeth Stuckey-French.
This lively, intricately plotted, laugh-out-loud funny, and surprisingly touching family drama combines the wit of Carl Hiaasen with the southern charm of Jill McCorkle.
Seventy-seven-year-old Marylou Ahearn is going to kill Dr. Wilson Spriggs come hell or high water. In 1953, he gave her a radioactive cocktail without her consent as part of a secret government study that had horrible consequences.
Marylou has been plotting her revenge for fifty years. When she accidentally discovers his whereabouts in Florida, her plans finally snap into action. She high tails it to hot and humid Tallahassee, moves in down the block from where a now senile Spriggs lives with his daughter's family, and begins the tricky work of insinuating herself into their lives. But she has no idea what a nest of yellow jackets she is stumbling into.
Before the novel is through, someone will be kidnapped, an unlikely couple will get engaged, someone will nearly die from eating a pineapple upside-down cake laced with anti-freeze, and that's not all . . .
Told from the varied perspectives of an incredible cast of endearing oddball characters and written with the flair of a native Floridian, this dark comedy does not disappoint.