I don't think the resolution of the screen is the only factor. The size is also a factor. If we have flexible screens in the future, so they can be folded and carried in a smaller space, fixed page sizes might work. But even with very high resolution displays, smaller screens displaying a full letter or A4 page won't work for everyone, and panning is not always a solution, especially for multicolumn formats. I don't think one solution will work for every non-fiction document.
And I agree with kovidgoyal, page images lose much of the value of digital reading.
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