I am a Mac fan - MacBook Pro - and a SONY PRS-505 happy owner. To use PC-only applications I installed Parrallels on my Mac and it works wonderfully. With its [Coherence] feature, it becomes seamless to me if I am opening a Mac or PC application.
In other words, I open the ebook Library application from Sony directly from Mac OS, and I don't even notice that Parallels launched Windows to open it.
I hope this helps,